Overview:
You have Excel 2016 and try to change the default save location to a SharePoint location and get error:
“Cannot access directory ‘http://myserver/mydoclib’
The setting is on the Excel Options Window, Save section, “Default local file location:” (see picture below)
Cause:
For some unknown reason, some Office 2016 installs fail to create a needed directory.
Workaround:
Add this directory to the systems experiencing the problem:
C:\Users\<userid>\AppData\Roaming\Microsoft\Excel\URL\
For example:
C:\Users\warren\AppData\Roaming\Microsoft\Excel\URL\